Plasma Pharmacokinetics of Topical 0.1% Diclofenac Sodium and 0.5% Ketorolac Tromethamine in Dogs

Diclofenac and ketorolac were rapidly absorbed systemically after ophthalmic administration. The half-life of topical ketorolac is six times longer than that of diclofenac.

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Publication Details

Journal
Veterinary Ophthalmology
Published
2025-11-12
DOI
https://doi.org/10.1111/vop.70105
Citations
1
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
1.39
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article

Plasma Pharmacokinetics of Topical 0.1% Diclofenac Sodium and 0.5% Ketorolac Tromethamine in Dogs

Vernon C. Langston, Danielle Fischer, Matthew K. Ross, Caroline M. Betbeze et al.
1 citations
Veterinary Ophthalmology
Inflammatory mediators and NSAID effects
1.39
article

Plasma Pharmacokinetics of Topical 0.1% Diclofenac Sodium and 0.5% Ketorolac Tromethamine in Dogs

Vernon C. Langston, Danielle Fischer, Matthew K. Ross, Caroline M. Betbeze, Robert P. Wills, Christine Cassen, Jacqueline Peraza
article en
1 citations

Abstract

Diclofenac and ketorolac were rapidly absorbed systemically after ophthalmic administration. The half-life of topical ketorolac is six times longer than that of diclofenac.

Veterinary OphthalmologyVol. 29(2)
Mississippi State University (US)
Openalex Percentile: Top 14%
Inflammatory mediators and NSAID effects
1.39
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