Impact of the lipid–inflammation axis on endometriosis risk: a multicenter case–control study using mediation analysis
Dyslipidemia may contribute to the development of EM through systemic inflammation, with SII serving as a potential intermediate marker. These findings suggest the potential value of integrating lipid regulation and anti-inflammatory strategies for EM prevention, although further clinical validation is warranted.
Authors
- Fanjun Kong (ORCID: https://orcid.org/0009-0005-1478-5851)
- Zhaoxia Ding (ORCID: https://orcid.org/0000-0003-1022-2531)
- Yushuang Yao
- Yiqing Peng
- Yanan Duan (ORCID: https://orcid.org/0009-0004-5211-5341)
- Aiping Chen (ORCID: https://orcid.org/0000-0002-7326-9444)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Community Health Center (US)
- Affiliated Hospital of Jining Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3389/fendo.2025.1661264
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00