Enterolactone promotes efficacy of gemcitabine on epithelial ovarian cancer and ameliorates gut dysbacteriosis
ENL and Gem synergistically inhibit the proliferation, migration, invasion, and angiogenesis of EOC by modulating the Akt-Bax and Akt-MMP9-VEGFR-2 pathways and ameliorating gut dysbacteriosis.
Authors
- Lingjie Luo (ORCID: https://orcid.org/0009-0001-8595-4342)
- Huidi Liu (ORCID: https://orcid.org/0000-0002-1884-0898)
- Xiaoyu Wang (ORCID: https://orcid.org/0000-0001-6548-3793)
- Caiji Lin (ORCID: https://orcid.org/0000-0002-1255-5703)
- Mengzhi Xu (ORCID: https://orcid.org/0000-0002-0400-3191)
- Danli Cao (ORCID: https://orcid.org/0000-0002-9859-3013)
- Yufan Zhao (ORCID: https://orcid.org/0009-0004-6603-1296)
- Xiaohui Xu (ORCID: https://orcid.org/0009-0003-9357-3413)
- Yan Yu (ORCID: https://orcid.org/0000-0003-0515-7747)
- Shu‐Lin Liu (ORCID: https://orcid.org/0000-0002-6883-6037)
- Qinghai Li
- Yi Guo (ORCID: https://orcid.org/0000-0002-3369-5385)
- Jiaxing Wang (ORCID: https://orcid.org/0000-0002-6674-4948)
- Jiayu Wei
- Wenxue Wang (ORCID: https://orcid.org/0000-0002-9865-6811)
- Shuang Wang (ORCID: https://orcid.org/0000-0002-2166-9091)
- Shimenghui Deng
- Shuhui Chai
- Xin Kang (ORCID: https://orcid.org/0000-0003-1258-4827)
Institutions
- Harbin Medical University (CN)
- University of Calgary (CA)
- Heilongjiang Academy of Sciences (CN)
- Institute of Zoology (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1111/bph.70241
- Primary Topic
- Potato Plant Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00