Development of cellular models expressing cynomolgus (Macaca fascicularis) HER2 for the functional evaluation of cross-reactive anti-human HER2 response
The results suggest that this model could be a promising tool for preclinical functional cross-reactivity tests of anti-HER2 therapies before <i>in vivo</i> studies.
Authors
- Stefania Angelicola
- Patrizia Nanni (ORCID: https://orcid.org/0000-0001-5319-0803)
- Maria Sofia Semprini (ORCID: https://orcid.org/0000-0001-5013-6908)
- Mette Thorn
- Arianna Palladini (ORCID: https://orcid.org/0000-0001-6105-4895)
- Pier‐Luigi Lollini (ORCID: https://orcid.org/0000-0003-1702-4108)
- Francesca Ruzzi (ORCID: https://orcid.org/0000-0001-9555-3166)
- Laura Scalambra
- Chiara Cappello (ORCID: https://orcid.org/0000-0003-4320-1470)
- Olga Maria Pittino
- Julia Consoli
Institutions
- University of Pavia (IT)
- The Capital Region Pharmacy (DK)
- Azienda USL di Bologna (IT)
- Policlinico San Matteo Fondazione (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3389/fphar.2025.1675875
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00