Immune cell profiling of peripheral blood in long-term testicular germ cell tumor survivors
Our study demonstrates an association between both cisplatin-based chemotherapy and radiotherapy with specific immune cell populations, suggesting that these treatment modalities may exert long-term immunomodulatory effects.
Authors
- Michal Chovanec (ORCID: https://orcid.org/0000-0002-5653-2909)
- Daniela Světlovská
- Katarína Rejleková (ORCID: https://orcid.org/0000-0002-2142-3411)
- Katarína Kaľavská
- Beáta Mladosievičová
- Michal Mego (ORCID: https://orcid.org/0000-0002-6511-6827)
- Andrea Mlcakova
- Zuzana Šestáková (ORCID: https://orcid.org/0000-0003-3229-0404)
- Valentina De Angelis
- Peter Lesko (ORCID: https://orcid.org/0000-0003-0205-4507)
- Jana Obertová
- Patrik Palacka (ORCID: https://orcid.org/0000-0003-4505-0952)
- Liang Cheng (ORCID: https://orcid.org/0009-0004-2260-6254)
- Zuzana Syčová-Milá
- Zuzana Orszaghova
- Kristyna Adamikova
- Kristina Kilikova
Institutions
- University of Trnava (SK)
- Slovak Medical University (SK)
- Slovak Academy of Sciences (SK)
- Brown University (US)
- National Institute of Cardiovascular Diseases (SK)
- Biomedical Research Center of the Slovak Academy of Sciences (SK)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1697087
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky
- Agentúra na Podporu Výskumu a Vývoja
- Vedecká Grantová Agentúra MŠVVaŠ SR a SAV