Crystal structure and Hirshfeld surface analysis of anhydrous salt of levofloxacin and 4-methylbenzoic acid
The anhydrous salt levofloxacinium 4-methyl-benzoate, C<sub>18</sub>H<sub>21</sub>FN<sub>3</sub>O<sub>4</sub> <sup>+</sup>·C<sub>8</sub>H<sub>7</sub>O<sub>2</sub> <sup>-</sup>, has been synthesized and its crystal structure determined. In the crystal, the levofloxacinium ions inter-act with the 4-methyl-benzoate anion <i>via</i> N-H<sup>+</sup>⋯O<sup>-</sup> and C-H⋯O hydrogen bonds, forming a tape-like supra-molecular structure. Hirshfeld surface analysis and the calculated two-dimensional finger plots of the various atom-atom contacts involving both the ions are described.
Authors
- J. Prakasha Reddy (ORCID: https://orcid.org/0000-0003-4550-2525)
- Krunal Modi (ORCID: https://orcid.org/0000-0002-1151-1207)
- Bhumiben Chandubhai Patel (ORCID: https://orcid.org/0000-0003-2836-0254)
Institutions
- Indrashil University (IN)
- Central University of Gujarat (IN)
Publication Details
- Journal
- Acta Crystallographica Section E Crystallographic Communications
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1107/s2056989025010047
- Primary Topic
- Crystallography and molecular interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Central University of Gujarat