Outcomes for patients with high-risk ER-positive, HER2-negative early-stage breast cancer: a Danish real-world study

A considerable proportion of Danish EBC patients meet high-risk criteria similar to CDK4/6 inhibitor trial populations and experience inferior outcomes despite standard therapy of antihormone treatment +/- chemotherapy. Our real-world data underscore the need for more effective and less toxic adjuvant therapies such as CDK4/6 inhibitors.

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Publication Details

Journal
Acta Oncologica
Published
2025-11-12
DOI
https://doi.org/10.2340/1651-226x.2025.44003
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes for patients with high-risk ER-positive, HER2-negative early-stage breast cancer: a Danish real-world study

Maj‐Britt Jensen, Ida Christine Jacobsen, Tobias Berg, Ann Søegaard Knop
Acta Oncologica
Advanced Breast Cancer Therapies
article

Outcomes for patients with high-risk ER-positive, HER2-negative early-stage breast cancer: a Danish real-world study

Maj‐Britt Jensen, Ida Christine Jacobsen, Tobias Berg, Ann Søegaard Knop
article en

Abstract

A considerable proportion of Danish EBC patients meet high-risk criteria similar to CDK4/6 inhibitor trial populations and experience inferior outcomes despite standard therapy of antihormone treatment +/- chemotherapy. Our real-world data underscore the need for more effective and less toxic adjuvant therapies such as CDK4/6 inhibitors.

Acta OncologicaVol. 64
Copenhagen University Hospital (DK), Rigshospitalet (DK), Danish Breast Cancer Cooperative Group (DK)
Openalex Percentile: Top 51%
Advanced Breast Cancer Therapies
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