Assessment of serum diagnostic biomarkers for periprosthetic joint infection in hip and knee arthroplasty: a retrospective study
The best diagnostic performance was achieved by CRP and FIB, and we recommend that these tests should be prioritized. Serum WBC, PC/MPV and PLT were insufficient to predict PJI prior to reimplantation arthroplasty of the hip and knee; however, CRP combined with FIB or PC/MPV best serves to obtain the most accurate prediction of PJI in our study.
Authors
- Xiaohe Wang (ORCID: https://orcid.org/0000-0001-9650-5721)
- Changcheng Hua
- Fei Yang (ORCID: https://orcid.org/0000-0003-3074-6973)
- Qiqi Zhang (ORCID: https://orcid.org/0000-0002-0734-7328)
- Hui Ma (ORCID: https://orcid.org/0000-0003-4272-1415)
- Zhiqiang Sun
Institutions
- Bozhou People's Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-11-13
- DOI
- https://doi.org/10.7717/peerj.20294
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00