Economic evaluation of different haematological monitoring schemes for patients with treatment-resistant schizophrenia using clozapine

A revision of current UK clozapine monitoring practice would be beneficial from both a clinical and an economic perspective. Adjusting ANC criteria for clozapine cessation avoids unnecessary early discontinuation of clozapine treatment and has a positive impact on quality of life. An extension of monitoring intervals reduces costs borne by the healthcare system. Safety is not compromised by these changes.

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Publication Details

Journal
The British Journal of Psychiatry
Published
2025-11-13
DOI
https://doi.org/10.1192/bjp.2025.10424
Citations
1
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Economic evaluation of different haematological monitoring schemes for patients with treatment-resistant schizophrenia using clozapine

David Taylor, Christian Bachmann, Ebenezer Oloyede, Freya Diederich
1 citations
The British Journal of Psychiatry
Schizophrenia research and treatment
1.47
article

Economic evaluation of different haematological monitoring schemes for patients with treatment-resistant schizophrenia using clozapine

David Taylor, Christian Bachmann, Ebenezer Oloyede, Freya Diederich
article en
1 citations

Abstract

A revision of current UK clozapine monitoring practice would be beneficial from both a clinical and an economic perspective. Adjusting ANC criteria for clozapine cessation avoids unnecessary early discontinuation of clozapine treatment and has a positive impact on quality of life. An extension of monitoring intervals reduces costs borne by the healthcare system. Safety is not compromised by these changes.

The British Journal of Psychiatry
University of Bremen (DE), King's College London (GB), Universität Ulm (DE), University of Oxford (GB), Maudsley Hospital (GB), University Hospital Ulm (DE), Technische Hochschule Ulm (DE)
Openalex Percentile: Top 14%
Schizophrenia research and treatment
1.47
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Economic evaluation of different haematological monitoring schemes for patients with treatment-resistant schizophrenia using clozapine — David Taylor, Christian Bachmann, et al. · The British Journal of Psychiatry (2025) | TGRS Research Map | TGRS