Two new macrocyclic cembrane diterpenoids from <i>Boswellia seratta</i> gum resin

Two previously undescribed macrocyclic diterpenoids, cycloserratol (<b>1</b>) and isopapyrifuranol A (<b>2</b>) were isolated from the gum resin of <i>Boswellia seratta.</i> Compound <b>1</b> was confirmed as trihydroxy substituted 12-membered macrocyclic cembrane-type diterpenoid skeleton and <b>2</b> was a new 1,12-oxygen fused trihydroxy cembrane skeleton. The structures of these new metabolites were characterized by HRESIMS, 1D NMR and 2D NMR analysis.

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Publication Details

Journal
Journal of Asian Natural Products Research
Published
2025-11-13
DOI
https://doi.org/10.1080/10286020.2025.2583447
Primary Topic
Pharmacological Effects of Medicinal Plants
Type
article
Field-Weighted Citation Impact
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article

Two new macrocyclic cembrane diterpenoids from Boswellia seratta gum resin

Raveendra Babu Kothapalli, Ramarao Paidi, Ramakrishna Singuru, Durgaprasad Metta
Journal of Asian Natural Products Research
Pharmacological Effects of Medicinal Plants
article

Two new macrocyclic cembrane diterpenoids from Boswellia seratta gum resin

Raveendra Babu Kothapalli, Ramarao Paidi, Ramakrishna Singuru, Durgaprasad Metta
article en

Abstract

Two previously undescribed macrocyclic diterpenoids, cycloserratol (<b>1</b>) and isopapyrifuranol A (<b>2</b>) were isolated from the gum resin of <i>Boswellia seratta.</i> Compound <b>1</b> was confirmed as trihydroxy substituted 12-membered macrocyclic cembrane-type diterpenoid skeleton and <b>2</b> was a new 1,12-oxygen fused trihydroxy cembrane skeleton. The structures of these new metabolites were characterized by HRESIMS, 1D NMR and 2D NMR analysis.

Journal of Asian Natural Products Research
Republic Polytechnic (SG), Ambedkar University Delhi (IN), Government of the United States of America (US), Institute for Government (GB), Government Medical College (IN)
Openalex Percentile: Top 62%
Pharmacological Effects of Medicinal Plants
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