Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer’s disease

In AD patients with ID, there may be both a direct and an indirect association between <i>Bifidobacterium</i> and sleep quality, with thalamic glucose metabolism mediating the indirect association, indicating that treatments aimed at enhancing brain metabolism and probiotic supplementation may improve sleep quality in this population.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-11-13
DOI
https://doi.org/10.3389/fneur.2025.1669835
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer’s disease

Chunbo Dong, Fangfang Jing, Jianwen Chen, Jinghui Xie et al.
Frontiers in Neurology
Gut microbiota and health
article

Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer’s disease

Chunbo Dong, Fangfang Jing, Jianwen Chen, Jinghui Xie, Jian Kang, Shiqi Zhao, Peixue Li
article en

Abstract

In AD patients with ID, there may be both a direct and an indirect association between <i>Bifidobacterium</i> and sleep quality, with thalamic glucose metabolism mediating the indirect association, indicating that treatments aimed at enhancing brain metabolism and probiotic supplementation may improve sleep quality in this population.

Frontiers in NeurologyVol. 16
Dalian Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN)
Openalex Percentile: Top 70%
Gut microbiota and health
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Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer’s disease — Chunbo Dong, Fangfang Jing, et al. · Frontiers in Neurology (2025) | TGRS Research Map | TGRS