Efflux-Mediated Macrolide Resistance in Clinical Streptococcus Isolates: A Comparative Molecular Study
This study provides the first molecular characterization of efflux-mediated macrolide resistance in UAE <i>Streptococcus</i> isolates. The predominance of <i>mef(A/E)</i>-mediated resistance with confirmed efflux activity highlights the clinical significance of active surveillance and targeted antimicrobial stewardship in the region.
Authors
- Einas A. Osman (ORCID: https://orcid.org/0000-0003-2567-889X)
- Praveen Kumar Kandakurti (ORCID: https://orcid.org/0000-0003-2669-4488)
- Salma Elnour Rahma Mohamed (ORCID: https://orcid.org/0000-0001-6439-5062)
- Shamsun Nahar Ahmed (ORCID: https://orcid.org/0000-0001-6416-0132)
- Sarah Ali (ORCID: https://orcid.org/0000-0002-6149-0467)
- Nour A. M. Farajallah (ORCID: https://orcid.org/0000-0002-1750-9773)
- Abdelgadir Alamin Altoum (ORCID: https://orcid.org/0000-0002-2442-2756)
- Salsabeel M. Moshewh (ORCID: https://orcid.org/0009-0003-7901-2572)
- Supriya R. Jagdale
Institutions
- Gulf Medical University (AE)
- Shaqra University (SA)
- Omdurman Ahlia University (SD)
- Thumbay Group (United Arab Emirates) (AE)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3390/antibiotics14111148
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gulf Medical University