Non-Lethal heat shock induces COMMD gene activation and enhances pathogen defense in Procambarus clarkii
This study demonstrates that COMMD8 is a critical regulator of stress-induced immune responses in P. clarkii, mediating enhanced resistance through modulation of innate immune signaling. These findings offer new insights into the function of COMMD proteins in crustaceans and contribute to a better understanding of how environmental stress influences invertebrate immunity.
Authors
- Zhangxuan Chen
- Shunchang Wang (ORCID: https://orcid.org/0000-0003-1513-2017)
- Shijing Yue (ORCID: https://orcid.org/0000-0002-9155-488X)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-9339-5667)
- Yulong Sun (ORCID: https://orcid.org/0000-0002-6811-5926)
- Xiuhong Cai
Institutions
- Anhui University of Science and Technology (CN)
- Zhejiang Ocean University (CN)
- Huainan Normal University (CN)
- Anhui and Huaihe River Institute of Hydraulic Research (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1186/s12864-025-12205-5
- Primary Topic
- Invertebrate Immune Response Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Huainan Normal University
- University Natural Science Research Project of Anhui Province
- Key Technologies Research and Development Program