Efficacy and Limitations of Flow Cytometry for the Rapid Diagnosis of Primary Central Nervous System Lymphoma
FCM yields reliable diagnostic information within hours of tissue collection and supports early therapeutic decisions in PCNSL. Discordant results may reflect reactive T-cell infiltration. This is the first study to present detailed subset analyses in PCNSL using FCM in correlation with pathology, underscoring its utility as a rapid diagnostic tool.
Authors
- Katsunori Yanagihara (ORCID: https://orcid.org/0000-0003-3677-2486)
- Yasushi Miyazaki
- Koji Ando (ORCID: https://orcid.org/0000-0001-7607-4899)
- Hiroo Hasegawa (ORCID: https://orcid.org/0000-0002-1822-5692)
- Ayaka Matsuo
- Kenta Ujifuku (ORCID: https://orcid.org/0000-0003-3481-8508)
- Masahiro Nakashima (ORCID: https://orcid.org/0000-0002-9036-8735)
- Michiharu Yoshida
- Hikaru Nakamura (ORCID: https://orcid.org/0000-0002-1864-1645)
- Takeshi Hiu (ORCID: https://orcid.org/0000-0001-7090-1662)
- Yukishige Hayashi
- Shiro Baba (ORCID: https://orcid.org/0000-0002-4170-1802)
- Takeharu Kato (ORCID: https://orcid.org/0000-0002-6137-890X)
- Koichi Yoshida (ORCID: https://orcid.org/0000-0003-3220-5038)
- Nozomi Ueki
- Hirofumi Koike
- Takayuki Matsuo (ORCID: https://orcid.org/0000-0003-0049-3346)
Institutions
- Nagasaki Prefectural Shimabara High School (JP)
- Nagasaki University Hospital (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3390/cancers17223646
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00