The Impact of Intranasal Esketamine on Emergence Agitation in Children Undergoing Adenotonsillectomy: A Randomized Controlled Study
Intranasal esketamine at a dose of 0.5 mg/kg significantly reduces the incidence of EA following pediatric adenotonsillectomy. Increasing the dose to 1 mg/kg does not confer additional benefit in preventing EA and may instead delay extubation.
Authors
- Ruixian Wang
- Gaili Jia
- Kaiming Yuan (ORCID: https://orcid.org/0000-0002-9660-8218)
- Jiajia Li (ORCID: https://orcid.org/0000-0002-1011-4568)
- Ruofang Zheng
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/dddt.s553693
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00