Semaglutide from Bench to Bedside: The Experimental Journey Towards a Transformative Therapy for Diabetes, Obesity and Metabolic Liver Disorders

The trajectory of semaglutide exemplifies how intentional peptide design, iterative translational research, and outcome-driven clinical trial design can lead to groundbreaking therapies for complex metabolic disorders.

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Publication Details

Journal
Medical Sciences
Published
2025-11-12
DOI
https://doi.org/10.3390/medsci13040265
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Semaglutide from Bench to Bedside: The Experimental Journey Towards a Transformative Therapy for Diabetes, Obesity and Metabolic Liver Disorders

Ralf Weiskirchen, Amedeo Lonardo
Medical Sciences
Diabetes Treatment and Management
article

Semaglutide from Bench to Bedside: The Experimental Journey Towards a Transformative Therapy for Diabetes, Obesity and Metabolic Liver Disorders

Ralf Weiskirchen, Amedeo Lonardo
article en

Abstract

The trajectory of semaglutide exemplifies how intentional peptide design, iterative translational research, and outcome-driven clinical trial design can lead to groundbreaking therapies for complex metabolic disorders.

Medical SciencesVol. 13(4)
Azienda Unita' Sanitaria Locale Di Modena (IT), Universitätsklinikum Aachen (DE), RWTH Aachen University (DE)
Openalex Percentile: Top 54%
Diabetes Treatment and Management
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