PEDF Alleviates Diabetic Renal Fibrosis by Degrading Kidney Ectopic Fat Deposition and Inhibiting Metabolic Reprogramming of Renal Tubular Epithelial Cells

PEDF can reduce abnormal renal fat accumulation and regulate metabolic reprogramming of renal tubular epithelial cells, thereby alleviating diabetic renal fibrosis.

Authors

Yan Bao
Tuohua Mao
Yingying Bi (ORCID: https://orcid.org/0009-0001-8964-4595)

Institutions

Wuhan University (CN)
Renmin Hospital of Wuhan University (CN)

Publication Details

Journal: Diabetes Metabolic Syndrome and Obesity
Published: 2025-11-01
DOI: https://doi.org/10.2147/dmso.s536576
Primary Topic: Chronic Kidney Disease and Diabetes
Type: article
Field-Weighted Citation Impact: 0.00

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article

PEDF Alleviates Diabetic Renal Fibrosis by Degrading Kidney Ectopic Fat Deposition and Inhibiting Metabolic Reprogramming of Renal Tubular Epithelial Cells

Yan Bao, Tuohua Mao, Yingying Bi

Nov 1, 2025

Diabetes Metabolic Syndrome and Obesity

Chronic Kidney Disease and Diabetes

article

PEDF Alleviates Diabetic Renal Fibrosis by Degrading Kidney Ectopic Fat Deposition and Inhibiting Metabolic Reprogramming of Renal Tubular Epithelial Cells

Yan Bao, Tuohua Mao, Yingying Bi

November 1, 2025article en

Abstract

PEDF can reduce abnormal renal fat accumulation and regulate metabolic reprogramming of renal tubular epithelial cells, thereby alleviating diabetic renal fibrosis.

Diabetes Metabolic Syndrome and ObesityVol. Volume 18

Wuhan University (CN), Renmin Hospital of Wuhan University (CN)

Openalex Percentile: Top 59%

Chronic Kidney Disease and Diabetes

DOI Open Access PDF OpenAlex

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PEDF Alleviates Diabetic Renal Fibrosis by Degrading Kidney Ectopic Fat Deposition and Inhibiting Metabolic Reprogramming of Renal Tubular Epithelial Cells — Yan Bao, Tuohua Mao, et al. · Diabetes Metabolic Syndrome and Obesity (2025) | TGRS Research Map | TGRS