Ultraprocessed Food Consumption and Risk of Early-Onset Colorectal Cancer Precursors Among Women
In this study, higher UPF intake was associated with increased risk of early-onset colorectal conventional adenomas. These data highlight the important role of UPFs in early-onset colorectal tumorigenesis and support improving dietary quality as a strategy to mitigate the increasing burden of EOCRC.
Authors
- Mingyang Song (ORCID: https://orcid.org/0000-0002-1324-0316)
- Edward L. Giovannucci (ORCID: https://orcid.org/0000-0002-6123-0219)
- Neha Khandpur (ORCID: https://orcid.org/0000-0002-4766-8361)
- Xiaoyu Zong (ORCID: https://orcid.org/0000-0001-5646-710X)
- Sarah Berry (ORCID: https://orcid.org/0000-0002-5819-5109)
- Emily R. Leeming (ORCID: https://orcid.org/0000-0002-0531-4901)
- David Drew (ORCID: https://orcid.org/0000-0001-8866-6349)
- Hanseul Kim (ORCID: https://orcid.org/0000-0002-5102-6118)
- Andrew T. Chan (ORCID: https://orcid.org/0000-0001-7284-6767)
- Qiao-Li Wang (ORCID: https://orcid.org/0000-0003-4152-7821)
- Shuji Ogino (ORCID: https://orcid.org/0000-0002-3909-2323)
- Kimmie Ng (ORCID: https://orcid.org/0000-0003-0631-1494)
- Tae‐Geun Gweon (ORCID: https://orcid.org/0000-0002-0884-7228)
- Yin Cao (ORCID: https://orcid.org/0000-0002-4821-3879)
- Chen Wang (ORCID: https://orcid.org/0000-0003-2638-3081)
- Long H. Nguyen (ORCID: https://orcid.org/0000-0002-5436-4219)
- Mengxi Du (ORCID: https://orcid.org/0000-0002-6406-7250)
- Qi Sun (ORCID: https://orcid.org/0009-0001-3262-9802)
Institutions
- Broad Institute (US)
- Tokyo Medical and Dental University (JP)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Universidade de São Paulo (BR)
- King's College London (GB)
- Washington University in St. Louis (US)
- Massachusetts General Hospital (US)
- Dana-Farber Cancer Institute (US)
- Dana-Farber/Harvard Cancer Center (US)
- Alvin J. Siteman Cancer Center (US)
- Catholic University of Korea (KR)
- Wageningen University & Research (NL)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1001/jamaoncol.2025.4777
- Citations
- 10
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 10.45