Preliminary efficacy and safety profile of dual histamine blockade on preventing filgrastim‐associated bone pain in breast cancer patients: Randomized controlled trial
The prophylactic dual histamine blockade strategy, when administered alongside filgrastim, could significantly ameliorate the incidence and severity of G-CSF-associated bone pain, and therefore improve patient's QoL. Further larger clinical studies are warranted to validate the clinical utility of this novel approach.
Authors
- Michael K. Mansour (ORCID: https://orcid.org/0000-0001-8892-8695)
- Mona Mohammed El‐Tamalawy (ORCID: https://orcid.org/0000-0002-7535-3674)
- Abdelrahman Yousef (ORCID: https://orcid.org/0000-0001-7761-8149)
- Noha O. Mansour (ORCID: https://orcid.org/0000-0002-4448-994X)
- Mostafa Abdelhakem
Institutions
- Mansoura University (EG)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1002/bcp.70327
- Primary Topic
- Lymphatic System and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00