<i>PRRX1</i> Orchestrates Pericyte–Myofibroblast Transition in Pathological Retinal Fibrosis

PRRX1 is a key regulator of pericyte-mediated fibrotic remodeling in the retina. Targeting PRRX1 offers a potential therapeutic approach for retinal fibrosis.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-11-13
DOI
https://doi.org/10.1167/iovs.66.14.24
Citations
1
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
1.71
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article

PRRX1 Orchestrates Pericyte–Myofibroblast Transition in Pathological Retinal Fibrosis

Jianing Qiu, Zhishang Meng, Yongan Meng, Bin Yan et al.
1 citations
Investigative Ophthalmology & Visual Science
Glaucoma and retinal disorders
1.71
article

PRRX1 Orchestrates Pericyte–Myofibroblast Transition in Pathological Retinal Fibrosis

Jianing Qiu, Zhishang Meng, Yongan Meng, Bin Yan, Youling Liang, Dan Liu, Weisong Shi, Jing Luo, Biying Chen, Jincai He, Yuqian Hu
article en
1 citations

Abstract

PRRX1 is a key regulator of pericyte-mediated fibrotic remodeling in the retina. Targeting PRRX1 offers a potential therapeutic approach for retinal fibrosis.

Investigative Ophthalmology & Visual ScienceVol. 66(14)
Central South University (CN), Second Xiangya Hospital of Central South University (CN)
Openalex Percentile: Top 12%
Glaucoma and retinal disorders
1.71
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