Biological analysis of Sonchus oleraceus (Linn) extract and its effect on mitigating sodium benzoate-induced cytotoxicity and genotoxicity

The results indicate that the aqueous extract of <i>S. oleraceus</i> leaves, as a single treatment, induces a genotoxic effect on <i>A. cepa</i> cells, especially at high concentrations, and that <i>S. oleraceus</i> leaf extract, as a co-treatment, acts as a mutagen at high concentrations and a moderate antimutagenic at low concentrations. The findings also indicate that the cytotoxic capacity of SB in <i>A. cepa</i> highlights potential concerns that warrant further investigation.

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Publication Details

Journal
Frontiers in Toxicology
Published
2025-11-13
DOI
https://doi.org/10.3389/ftox.2025.1674822
Primary Topic
Sesquiterpenes and Asteraceae Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Biological analysis of Sonchus oleraceus (Linn) extract and its effect on mitigating sodium benzoate-induced cytotoxicity and genotoxicity

Sameer H. Qari, Aljawharah Alqathama, Abdulmajeed F. Alrefaei, Maryam Abdulmalik Althubyani et al.
Frontiers in Toxicology
Sesquiterpenes and Asteraceae Studies
article

Biological analysis of Sonchus oleraceus (Linn) extract and its effect on mitigating sodium benzoate-induced cytotoxicity and genotoxicity

Sameer H. Qari, Aljawharah Alqathama, Abdulmajeed F. Alrefaei, Maryam Abdulmalik Althubyani, Rayan S. Alharbi
article en

Abstract

The results indicate that the aqueous extract of <i>S. oleraceus</i> leaves, as a single treatment, induces a genotoxic effect on <i>A. cepa</i> cells, especially at high concentrations, and that <i>S. oleraceus</i> leaf extract, as a co-treatment, acts as a mutagen at high concentrations and a moderate antimutagenic at low concentrations. The findings also indicate that the cytotoxic capacity of SB in <i>A. cepa</i> highlights potential concerns that warrant further investigation.

Frontiers in ToxicologyVol. 7
Umm al-Qura University (SA)
Umm Al-Qura University
Openalex Percentile: Top 58%
Sesquiterpenes and Asteraceae Studies
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Biological analysis of Sonchus oleraceus (Linn) extract and its effect on mitigating sodium benzoate-induced cytotoxicity and genotoxicity — Sameer H. Qari, Aljawharah Alqathama, et al. · Frontiers in Toxicology (2025) | TGRS Research Map | TGRS