Diagnostic efficacy and subgroup heterogeneity of SHOX2, RASSF1A, Septin9, and HOXA9 methylation in pleural effusion lymphoma
Integrating methylation markers SHOX2, HOXA9, Septin9, and RASSF1A exhibits significant diagnostic potential in pleural effusion lymphoma, especially within DLBCL subgroups. These markers could prove valuable in identifying high-risk subgroups and guiding clinical decision-making.
Authors
- Yu Zeng (ORCID: https://orcid.org/0000-0002-9415-0610)
- Xinxin Huang (ORCID: https://orcid.org/0000-0002-6695-5606)
- Bin She (ORCID: https://orcid.org/0000-0001-5147-0465)
- Xiaosha Ren
- Jiaqi Bo (ORCID: https://orcid.org/0000-0003-2266-0205)
- Weiwei Rui
- Jie Li (ORCID: https://orcid.org/0000-0002-3238-6847)
- Lei Zhang (ORCID: https://orcid.org/0009-0008-9783-092X)
- Shunli Wang (ORCID: https://orcid.org/0000-0003-0485-8082)
- Xianghua Yi (ORCID: https://orcid.org/0000-0002-5615-9331)
- Suxia Zhang (ORCID: https://orcid.org/0000-0002-1790-7958)
- Miaoxia He
Institutions
- Tongji University (CN)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Changzhi Medical College (CN)
- Ruijin Hospital (CN)
- Changhai Hospital (CN)
- Shanghai Huayi Group (China) (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s13148-025-01996-9
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00