Osteoporosis and fragility fractures in patients with acromegaly: A two-center cross-sectional study
A high prevalence of osteoporosis and fragility fractures was found in patients with acromegaly, regardless of age, sex, BMI, time from diagnosis, IGF-1 levels, and disease control. More patients with osteoporosis were treated with somatostatin analogs compared to those without osteoporosis. Taken together, our results suggest that the severity of the disease and the need for second-line therapies, may be associated with the increased risk of osteoporosis.
Authors
- Maria Mercedes Ulloa
- Oswaldo Rincón (ORCID: https://orcid.org/0000-0001-6871-2520)
- Alejandra Alvarado (ORCID: https://orcid.org/0000-0002-4673-4996)
- Liliana María Cardona Mejía (ORCID: https://orcid.org/0000-0002-3102-0683)
- Juliana Rincon
- Mónica Bernal (ORCID: https://orcid.org/0000-0003-1441-1903)
- Mauricio Álvarez (ORCID: https://orcid.org/0000-0003-3171-1043)
- Andrés Pereira
Institutions
- Hospital Militar Central (CO)
- Fundación Universitaria Sanitas (CO)
Publication Details
- Journal
- World Journal of Orthopedics
- Published
- 2025-11-14
- DOI
- https://doi.org/10.5312/wjo.v16.i11.110420
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00