Correlation of magnetic resonance imaging biomarkers (tissue bridges) with neurological recovery following traumatic spinal cord injury

The MRI imaging biomarkers in SCI patients demonstrated substantial improvement over time. There was a negative correlation between neurological recovery, MSCC, maximum canal compromise, and lesion dimensions (lesion length, lesion width, and lesion area). Higher canal compromise and lesion dimensions were associated with a poorer outcome. The evaluation of the midsagittal tissue bridge (including the ventral tissue bridge, dorsal tissue bridge, total width of the tissue bridge, and tissue bridge ratios) at 1 and 6 months showed a positive correlation with the neurological recovery.