Origin of chemo- and stereoselectivity in NHC-catalyzed asymmetric intermolecular cycloadditions of hydrazone and isatin

DFT was used to investigate the possible mechanisms of NHC-catalyzed asymmetric cycloadditions between hydrazones and isatins, including [4 + 2] and [3 + 2] cycloadditions.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-11-14
DOI
https://doi.org/10.1039/d5qo01408e
Citations
2
Primary Topic
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Type
article
Field-Weighted Citation Impact
1.87
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article

Origin of chemo- and stereoselectivity in NHC-catalyzed asymmetric intermolecular cycloadditions of hydrazone and isatin

Tingting Shen, Donghui Wei, Xinghua Wang, Ziyuan Zhou
2 citations
Organic Chemistry Frontiers
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
1.87
article

Origin of chemo- and stereoselectivity in NHC-catalyzed asymmetric intermolecular cycloadditions of hydrazone and isatin

Tingting Shen, Donghui Wei, Xinghua Wang, Ziyuan Zhou
article en
2 citations

Abstract

DFT was used to investigate the possible mechanisms of NHC-catalyzed asymmetric cycloadditions between hydrazones and isatins, including [4 + 2] and [3 + 2] cycloadditions.

Organic Chemistry FrontiersVol. 13(2)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Zhengzhou University (CN), Shangqiu Normal University (CN)
Openalex Percentile: Top 13%
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
1.87
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