Esophageal strictures: Management beyond dilation

Esophageal stricture refers to a pathological narrowing of the esophageal lumen, causing dysphagia and impairing the patient's quality of life. There are various etiologies including esophageal malignancy, peptic injury, caustic ingestion, post-surgical anastomosis, radiation therapy, and inflammatory disorders such as eosinophilic esophagitis. The primary goal in managing esophageal strictures is to relieve dysphagia by maintaining luminal patency. Endoscopic dilation remains the mainstay of treatment for most benign strictures, with either bougie or balloon dilators. For patients who develop refractory or recurrent strictures that are difficult to manage with dilation alone, adjunctive therapies like intralesional steroid injections, topical or injected mitomycin C, incisional therapy, stent placement, and finally surgery may enhance outcomes and reduce the frequency of repeat procedures. The present review focuses on the basics of dilation and adjunctive strategies for the management of esophageal stricture.

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Publication Details

Journal
World Journal of Gastrointestinal Endoscopy
Published
2025-11-14
DOI
https://doi.org/10.4253/wjge.v17.i11.110024
Primary Topic
Esophageal and GI Pathology
Type
article
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article

Esophageal strictures: Management beyond dilation

Rakesh Kochhar, Anupam Singh, Manish Manrai, Arjun Singh
World Journal of Gastrointestinal Endoscopy
Esophageal and GI Pathology
article

Esophageal strictures: Management beyond dilation

Rakesh Kochhar, Anupam Singh, Manish Manrai, Arjun Singh
article en

Abstract

Esophageal stricture refers to a pathological narrowing of the esophageal lumen, causing dysphagia and impairing the patient's quality of life. There are various etiologies including esophageal malignancy, peptic injury, caustic ingestion, post-surgical anastomosis, radiation therapy, and inflammatory disorders such as eosinophilic esophagitis. The primary goal in managing esophageal strictures is to relieve dysphagia by maintaining luminal patency. Endoscopic dilation remains the mainstay of treatment for most benign strictures, with either bougie or balloon dilators. For patients who develop refractory or recurrent strictures that are difficult to manage with dilation alone, adjunctive therapies like intralesional steroid injections, topical or injected mitomycin C, incisional therapy, stent placement, and finally surgery may enhance outcomes and reduce the frequency of repeat procedures. The present review focuses on the basics of dilation and adjunctive strategies for the management of esophageal stricture.

World Journal of Gastrointestinal EndoscopyVol. 17(11)
Post Graduate Institute of Medical Education and Research (IN)
Openalex Percentile: Top 47%
Esophageal and GI Pathology
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