Co-delivery of all- trans -retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles
Co-delivery of all-trans-retinoic acid and paclitaxel using albumin-bound nanoparticles demonstrated a significantly improved anti-metastatic effect to breast cancer both in vitro and in vivo. Notably, the co-delivery nanoparticles exhibited more pronounced therapeutic effects than the combination of two free drugs or two HSA loaded single drugs.
Authors
- Hai Huang (ORCID: https://orcid.org/0000-0003-2123-6533)
- Hongdong Shi
- Yucai Wang (ORCID: https://orcid.org/0000-0001-6046-2934)
- Andrew Z. Wang (ORCID: https://orcid.org/0000-0002-9781-4494)
- Yuanzeng Min (ORCID: https://orcid.org/0000-0001-5030-0210)
- Yangzhong Liu (ORCID: https://orcid.org/0000-0003-2891-7964)
- Jun Wang (ORCID: https://orcid.org/0000-0001-9957-9208)
- Jing Liu (ORCID: https://orcid.org/0000-0001-9513-3591)
Institutions
- University of North Carolina at Chapel Hill (US)
Publication Details
- Journal
- UNC Libraries
- Published
- 2025-03-01
- DOI
- https://doi.org/10.17615/vg4y-1b49
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00