Sodium–Glucose Cotransporter 2 Inhibitors, Glucagon-Like Peptide 1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes

GLP-1RAs and SGLT-2is may slow frailty progression through mechanisms independent of cardiovascular benefits. Future trials should confirm these preliminary findings.

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Publication Details

Journal
Diabetes Care
Published
2025-11-13
DOI
https://doi.org/10.2337/dc25-1031
Citations
2
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
2.59
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article

Sodium–Glucose Cotransporter 2 Inhibitors, Glucagon-Like Peptide 1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes

Gahee Oh, Saran Thanapluetiwong, Dae Hyun Kim, Chan Mi Park et al.
2 citations
Diabetes Care
Diabetes Treatment and Management
2.59
article

Sodium–Glucose Cotransporter 2 Inhibitors, Glucagon-Like Peptide 1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes

Gahee Oh, Saran Thanapluetiwong, Dae Hyun Kim, Chan Mi Park, Darae Ko, Xiaojun Chen
article en
2 citations

Abstract

GLP-1RAs and SGLT-2is may slow frailty progression through mechanisms independent of cardiovascular benefits. Future trials should confirm these preliminary findings.

Diabetes CareVol. 49(1)
Beth Israel Deaconess Medical Center (US), Harvard University (US), Hebrew SeniorLife (US), Ramathibodi Hospital (TH)
Openalex Percentile: Top 8%
Diabetes Treatment and Management
2.59
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Sodium–Glucose Cotransporter 2 Inhibitors, Glucagon-Like Peptide 1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes — Gahee Oh, Saran Thanapluetiwong, et al. · Diabetes Care (2025) | TGRS Research Map | TGRS