Dosimetric divergence in ICBT vs. IC/ISBT configurations: Comparative analysis of three optimization algorithms for cervical cancer brachytherapy

Inverse optimization effectively reduces doses to OARs while maintaining target coverage. HIPO appears to be the preferred choice for IC/ISBT, due to shortened treatment time, superior CI and rectal protection compared with IPSA.

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Publication Details

Journal
PLoS ONE
Published
2025-11-13
DOI
https://doi.org/10.1371/journal.pone.0335405
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Dosimetric divergence in ICBT vs. IC/ISBT configurations: Comparative analysis of three optimization algorithms for cervical cancer brachytherapy

Guohua Wang, Kaiqiang Chen, Jihong Chen, Xiuchun Zhang et al.
PLoS ONE
Endometrial and Cervical Cancer Treatments
article

Dosimetric divergence in ICBT vs. IC/ISBT configurations: Comparative analysis of three optimization algorithms for cervical cancer brachytherapy

Guohua Wang, Kaiqiang Chen, Jihong Chen, Xiuchun Zhang, Penggang Bai, Jiabiao Hong
article en

Abstract

Inverse optimization effectively reduces doses to OARs while maintaining target coverage. HIPO appears to be the preferred choice for IC/ISBT, due to shortened treatment time, superior CI and rectal protection compared with IPSA.

PLoS ONEVol. 20(11)
Fujian Medical University (CN), Fujian Provincial Cancer Hospital (CN), University of South China (CN)
Openalex Percentile: Top 57%
Endometrial and Cervical Cancer Treatments
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