Central autonomic nervous tract integrity of the brain is linked to blood pressure
This study provides evidence of a specific relationship between BP levels and the microstructural integrity of the CAN. We found that, particularly in cortical parts of the CAN, higher levels of free water - indicating tissue not actively involved in neural signalling - were associated with elevated BP levels and a greater risk of hypertension. This evidence supports a close link between the central autonomic system and BP from a population-imaging perspective.
Authors
- Horst Urbach (ORCID: https://orcid.org/0000-0001-7264-4807)
- Janis M. Nolde (ORCID: https://orcid.org/0000-0001-6864-8514)
- Fabian Bamberg (ORCID: https://orcid.org/0000-0002-7460-3942)
- Elias Kellner (ORCID: https://orcid.org/0000-0001-9494-2354)
- Marco Reisert (ORCID: https://orcid.org/0000-0003-2742-1940)
- Alexander Rau (ORCID: https://orcid.org/0000-0001-5881-6043)
- Jonas A. Hosp (ORCID: https://orcid.org/0000-0001-7696-9334)
- Jakob Weiss (ORCID: https://orcid.org/0000-0002-0336-8519)
- Heinz Wiendl (ORCID: https://orcid.org/0000-0001-5509-1075)
Institutions
- The University of Sydney (AU)
- University of Freiburg (DE)
- Society of Interventional Radiology (US)
Publication Details
- Journal
- Journal of Hypertension
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1097/hjh.0000000000004182
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00