Treatment sequences and lines of therapy in rheumatoid arthritis: a real-world evaluation of retention and effectiveness
This study offers insights into real-world sequential AT use in Canadian RA care. First-line AT is associated with superior survival and effectiveness; however, subsequent therapies continue to provide important clinical benefits. These findings support the value of personalised sequential treatment strategies and highlight the need for further research to inform future RA management guidelines.
Authors
- Sibel Zehra Aydın (ORCID: https://orcid.org/0000-0001-8792-4449)
- Mohammad Movahedi (ORCID: https://orcid.org/0000-0001-6154-0121)
- Pooneh Akhavan (ORCID: https://orcid.org/0000-0003-1882-7420)
- Bindee Kuriya (ORCID: https://orcid.org/0000-0003-3370-0006)
- Angela Cesta
- Xiuying Li (ORCID: https://orcid.org/0000-0001-5625-7591)
- Claire Bombardier
Institutions
- Ottawa Hospital (CA)
- Toronto General Hospital (CA)
- Toronto General Hospital Research Institute
- Ottawa Hospital Research Institute (CA)
Publication Details
- Journal
- Clinical and Experimental Rheumatology
- Published
- 2025-06-23
- DOI
- https://doi.org/10.55563/clinexprheumatol/y1vbr1
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00