Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring <scp> <i>GBA1</i> </scp> Variant
Findings from Japan's largest genetic cohort suggest that GBA1 variants may not significantly affect postoperative motor or cognitive trajectories following STN-DBS. Further validation through large-scale multinational and multicenter studies is warranted.
Authors
- Manabu Funayama (ORCID: https://orcid.org/0000-0002-7412-3631)
- Wataru Sako (ORCID: https://orcid.org/0000-0003-2009-2486)
- Genko Oyama (ORCID: https://orcid.org/0000-0001-7985-5367)
- Haruka Takeshige‐Amano (ORCID: https://orcid.org/0000-0003-3326-8559)
- Noriko Nishikawa (ORCID: https://orcid.org/0000-0001-7762-3597)
- Hikaru Kamo (ORCID: https://orcid.org/0000-0002-9408-7893)
- Taku Hatano (ORCID: https://orcid.org/0000-0002-6808-0444)
- Hirokazu Iwamuro (ORCID: https://orcid.org/0000-0002-9970-6331)
- Masanobu Ito (ORCID: https://orcid.org/0000-0001-7228-9809)
- Takashi Ogawa (ORCID: https://orcid.org/0000-0002-7335-0672)
- Yuanzhe Li (ORCID: https://orcid.org/0000-0002-3200-6701)
- Atsushi Umemura (ORCID: https://orcid.org/0000-0003-3229-4691)
- Hiroyo Yoshino (ORCID: https://orcid.org/0009-0002-6641-8728)
- Mai Shimizu
Institutions
- University of Florida (US)
- Juntendo University (JP)
- Juntendo University Urayasu Hospital (JP)
- Saitama Medical University (JP)
Publication Details
- Journal
- Movement Disorders Clinical Practice
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1002/mdc3.70411
- Citations
- 2
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78