GD2-CAR–Engineered Microglia Exhibit Antitumor Effects in Organoids and Animal Models of Retinoblastoma
Our findings demonstrate a potent antitumor effect of GD2-CAR-engineered microglia in retinoblastoma, offering compelling evidence to support the continued development of CAR-microglia as a therapeutic strategy for this disease.
Authors
- Yimeng Gao (ORCID: https://orcid.org/0000-0003-2954-2789)
- Zhibao Zhang
- Jia Xu (ORCID: https://orcid.org/0000-0003-0254-6261)
- Zi‐Bing Jin (ORCID: https://orcid.org/0000-0003-0515-698X)
- Ya Cheng (ORCID: https://orcid.org/0000-0001-8269-5907)
- Jinyi Wang (ORCID: https://orcid.org/0000-0002-5746-6165)
- Meng Lyv
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1167/iovs.66.14.26
- Citations
- 1
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39