Effectiveness of direct oral anticoagulants for all‐cause mortality and cardiovascular events in overweight and obese patients with atrial fibrillation: Insight from the nationwide START registry
In this nationwide registry, DOACs were associated with lower risks of mortality and CVEs compared with VKAs across BMI groups, though the CVE effect was not evident in obese patients. These findings suggest a potential mortality advantage of DOACs irrespective of BMI, warranting further confirmation.
Authors
- Gualtiero Palareti (ORCID: https://orcid.org/0000-0002-4327-9561)
- Daniele Pastori (ORCID: https://orcid.org/0000-0001-6357-5213)
- Danilo Menichelli (ORCID: https://orcid.org/0000-0001-9467-5903)
- Daniela Poli (ORCID: https://orcid.org/0000-0002-5166-6596)
- Gianluca Gazzaniga (ORCID: https://orcid.org/0000-0003-0648-3309)
- Emilia Antonucci (ORCID: https://orcid.org/0000-0001-9185-2046)
- Pasquale Pignatelli
Institutions
- Istituto Neurologico Mediterraneo (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- ANT Foundation Italy Onlus (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1111/eci.70148
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sapienza Università di Roma