Cardiac remodelling in novel cluster-based metabolic (dysfunction)-associated fatty liver disease: a cross-sectional study in China

The heterogeneity of MAFLD reveals sex-specific patterns of cardiac remodelling: male phenotypes with high BMI and uric acid levels are associated with worse remodelling, whereas a female phenotype characterised by high FIB-4 levels correlates with preserved cardiac function.

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Publication Details

Journal
BMJ Open
Published
2025-11-01
DOI
https://doi.org/10.1136/bmjopen-2025-102845
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Cardiac remodelling in novel cluster-based metabolic (dysfunction)-associated fatty liver disease: a cross-sectional study in China

Xiaolan Ouyang, Weilan Huang, X W Tang, Shangyan Liang et al.
BMJ Open
Liver Disease Diagnosis and Treatment
article

Cardiac remodelling in novel cluster-based metabolic (dysfunction)-associated fatty liver disease: a cross-sectional study in China

Xiaolan Ouyang, Weilan Huang, X W Tang, Shangyan Liang, Boxiong Jiang, Xiumei Tang, Sihui Luo, Ying Zhou, Na Ye, Yina Wang
article en

Abstract

The heterogeneity of MAFLD reveals sex-specific patterns of cardiac remodelling: male phenotypes with high BMI and uric acid levels are associated with worse remodelling, whereas a female phenotype characterised by high FIB-4 levels correlates with preserved cardiac function.

BMJ OpenVol. 15(11)
Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Sun Yat-sen University, Basic and Applied Basic Research Foundation of Guangdong Province
Openalex Percentile: Top 55%
Liver Disease Diagnosis and Treatment
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