Postinfectious Manifestation of Wilson’s Disease in COVID-19 Presenting as Writer’s Cramp: A Case Report
Wilson's disease (WD) is a neurometabolic disorder of copper metabolism with varied neurological presentations. COVID-19 has been associated with a multitude of multisystemic involvement, especially nervous system due to direct involvement, systemic inflammation, and immune-mediated phenomena. Movement disorders, however, represent a small domain of COVID-19 illness. A 23-year-old male developed behavioral changes, writer's cramp, and other neuropsychiatric symptoms following a COVID-19 infection, leading to a diagnosis of WD. Examination revealed Kayser-Fleischer rings and brain imaging abnormalities. Diagnosis was confirmed by low ceruloplasmin levels, elevated 24 h urine copper, and genetic testing. This case highlights the postinfectious manifestations of WD and its rare presentation as a writer's cramp.
Authors
- Rajarshi Chakraborty (ORCID: https://orcid.org/0000-0003-2304-2177)
- Rajesh Verma (ORCID: https://orcid.org/0000-0001-7016-2361)
- K. P. Arjun Bal
Institutions
- King George's Medical University (IN)
Publication Details
- Journal
- Acta Neurologica Taiwanica
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4103/ant.ant-d-24-00017
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00