Postinfectious Manifestation of Wilson’s Disease in COVID-19 Presenting as Writer’s Cramp: A Case Report

Wilson's disease (WD) is a neurometabolic disorder of copper metabolism with varied neurological presentations. COVID-19 has been associated with a multitude of multisystemic involvement, especially nervous system due to direct involvement, systemic inflammation, and immune-mediated phenomena. Movement disorders, however, represent a small domain of COVID-19 illness. A 23-year-old male developed behavioral changes, writer's cramp, and other neuropsychiatric symptoms following a COVID-19 infection, leading to a diagnosis of WD. Examination revealed Kayser-Fleischer rings and brain imaging abnormalities. Diagnosis was confirmed by low ceruloplasmin levels, elevated 24 h urine copper, and genetic testing. This case highlights the postinfectious manifestations of WD and its rare presentation as a writer's cramp.

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Publication Details

Journal
Acta Neurologica Taiwanica
Published
2025-10-01
DOI
https://doi.org/10.4103/ant.ant-d-24-00017
Primary Topic
Trace Elements in Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Postinfectious Manifestation of Wilson’s Disease in COVID-19 Presenting as Writer’s Cramp: A Case Report

Rajarshi Chakraborty, Rajesh Verma, K. P. Arjun Bal
Acta Neurologica Taiwanica
Trace Elements in Health
article

Postinfectious Manifestation of Wilson’s Disease in COVID-19 Presenting as Writer’s Cramp: A Case Report

Rajarshi Chakraborty, Rajesh Verma, K. P. Arjun Bal
article en

Abstract

Wilson's disease (WD) is a neurometabolic disorder of copper metabolism with varied neurological presentations. COVID-19 has been associated with a multitude of multisystemic involvement, especially nervous system due to direct involvement, systemic inflammation, and immune-mediated phenomena. Movement disorders, however, represent a small domain of COVID-19 illness. A 23-year-old male developed behavioral changes, writer's cramp, and other neuropsychiatric symptoms following a COVID-19 infection, leading to a diagnosis of WD. Examination revealed Kayser-Fleischer rings and brain imaging abnormalities. Diagnosis was confirmed by low ceruloplasmin levels, elevated 24 h urine copper, and genetic testing. This case highlights the postinfectious manifestations of WD and its rare presentation as a writer's cramp.

Acta Neurologica TaiwanicaVol. 34(4)
King George's Medical University (IN)
Openalex Percentile: Top 59%
Trace Elements in Health
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