Flow-through analytical systems and microsystems with electrochemical detection for monitoring of biologically active species (IUPAC Technical Report)

Abstract Requirements for cost and labor-effective quality control chemical analysis, which is friendly to environment and human health according to principles of green and white analytical chemistry, lead to challenges in instrumentations, their setup and testing methods. Low-cost and effective electrochemical detection platforms and procedures in flowing systems such as injection analysis, liquid chromatography, capillary electrophoresis, lab-on-a-chip and other devices have emerged as a simple and robust alternative to conventional tests. The technical report aims to address both current trends and future potential in this field for the development of new methods as well as fabrication and commercialization of the devices including miniaturization and portable assays realization under on-site, point-of-care, in-place, and field analyses. To achieve it, optimization and standardization of the flow-through systems and establishment of standardized testing protocols are of importance. Real application examples demonstrate the benefits of these systems developed with user-friendly interfaces for application in monitoring of biologically active species in biomedical diagnostics, and treatment, environmental protection, and food quality control.