Quality of life changes in cluster headache: Convergent validity, responsiveness, and interpretability of the Cluster Headache Quality of Life scale as a patient‐reported outcome measure
The CHQ has a high validity to measure change in QoL. CH attack frequency influences QoL, but QoL is more strongly correlated with mental health and activity restrictions than attack frequency. Implementing the CHQ may improve understanding of disease burden, enabling more targeted treatment strategies and thus improving overall disease management.
Authors
- Denise Bijlenga (ORCID: https://orcid.org/0000-0002-5169-9830)
- Wim M. Mulleners (ORCID: https://orcid.org/0000-0002-8039-2491)
- Roemer B. Brandt (ORCID: https://orcid.org/0000-0002-2932-4872)
- Erkan Kurt (ORCID: https://orcid.org/0000-0003-3768-4007)
- Leopoldine A. Wilbrink (ORCID: https://orcid.org/0000-0003-1226-1059)
- Willemijn C. Naber (ORCID: https://orcid.org/0000-0002-9260-9336)
- Rolf Fronczek (ORCID: https://orcid.org/0000-0002-1935-7603)
- Jeroen J. Jansen (ORCID: https://orcid.org/0009-0004-4420-7764)
- Frank J. P. M. Huygen
- Willemijn G. Leen
- Paulien J. van Tilborg (ORCID: https://orcid.org/0009-0001-9233-0538)
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- National Migraine Centre (GB)
- Canisius-Wilhelmina Ziekenhuis (NL)
- Zuyderland Medisch Centrum (NL)
- Stichting Epilepsie Instellingen Nederland (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Headache The Journal of Head and Face Pain
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1111/head.15083
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eli Lilly and Company
- Teva Pharmaceutical Industries
- Universiteit Leiden
- ZonMw
- H. Lundbeck A/S