Hyperreflective Ganglion Cell Layer Band in NCL3-Associated Retinal Degeneration

This report highlights a previously undescribed finding of a hyperreflective ganglion cell layer band in isolated NCL3-associated retinopathy, further expanding the spectrum of structural inner retinal changes seen in this condition and underscoring the role of Müller cell and ganglion cell involvement in the pathogenesis of NCL3-linked retinal degeneration.

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Publication Details

Journal
Retinal Cases & Brief Reports
Published
2025-09-29
DOI
https://doi.org/10.1097/icb.0000000000001825
Primary Topic
Lysosomal Storage Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hyperreflective Ganglion Cell Layer Band in NCL3-Associated Retinal Degeneration

Sheena Khanna, Alberto Quarta, Srinivas R. Sadda, Giulia Corradetti
Retinal Cases & Brief Reports
Lysosomal Storage Disorders Research
article

Hyperreflective Ganglion Cell Layer Band in NCL3-Associated Retinal Degeneration

Sheena Khanna, Alberto Quarta, Srinivas R. Sadda, Giulia Corradetti
article en

Abstract

This report highlights a previously undescribed finding of a hyperreflective ganglion cell layer band in isolated NCL3-associated retinopathy, further expanding the spectrum of structural inner retinal changes seen in this condition and underscoring the role of Müller cell and ganglion cell involvement in the pathogenesis of NCL3-linked retinal degeneration.

Retinal Cases & Brief Reports
University of Chieti-Pescara (IT), Doheny Eye Institute (US)
Openalex Percentile: Top 58%
Lysosomal Storage Disorders Research
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