Protein Inhibitor of Activated STAT2 Protects against Podocyte Injury in Diabetic Nephropathy via Inhibiting JAK2/STAT3 Pathway
PIAS2 plays a protective role in DN by inhibiting JAK2/STAT3 signaling pathway to alleviate high glucose-induced podocyte injury. PIAS2 may be a potential new target in the treatment of DN. .
Authors
- Xia Li (ORCID: https://orcid.org/0000-0003-2448-8859)
- Yanxia Zhang (ORCID: https://orcid.org/0000-0002-1920-6709)
Institutions
- Tongren Hospital (CN)
- Wuhan Third Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Kidney & Blood Pressure Research
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1159/000549274
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00