Interleukin-6 moderates the relationship between social support, strain, and future depressive symptoms

IL-6 levels may moderate the relationship between social support, strain, and future MDD symptoms. Interpersonally-focused interventions enhancing social support or mitigating strain may consider the potential interacting role of inflammation in alleviating the psychosocial risk of depression.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2025-10-15
DOI
https://doi.org/10.1016/j.bbih.2025.101122
Citations
2
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
1.16
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article

Interleukin-6 moderates the relationship between social support, strain, and future depressive symptoms

Tak Yee Aw, Nur Hani Zainal
2 citations
Brain Behavior & Immunity - Health
Tryptophan and brain disorders
1.16
article

Interleukin-6 moderates the relationship between social support, strain, and future depressive symptoms

Tak Yee Aw, Nur Hani Zainal
article en
2 citations

Abstract

IL-6 levels may moderate the relationship between social support, strain, and future MDD symptoms. Interpersonally-focused interventions enhancing social support or mitigating strain may consider the potential interacting role of inflammation in alleviating the psychosocial risk of depression.

Brain Behavior & Immunity - HealthVol. 49
National University of Singapore (SG)
Openalex Percentile: Top 20%
Tryptophan and brain disorders
1.16
DOIOpen Access PDFOpenAlex
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Interleukin-6 moderates the relationship between social support, strain, and future depressive symptoms — Tak Yee Aw, Nur Hani Zainal · Brain Behavior & Immunity - Health (2025) | TGRS Research Map | TGRS