Antiviral treatment response to nucleos(t)ide analogues in chronic hepatitis B patients with normal alanine aminotransferase levels: a retrospective multi-center study

CHB patients with normal ALT levels had comparable VR rates but significantly lower rates of HBeAg clearance and seroconversion during first-line NA therapy than patients with elevated ALT levels.

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Publication Details

Journal
Emerging Microbes & Infections
Published
2025-11-12
DOI
https://doi.org/10.1080/22221751.2025.2589550
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Antiviral treatment response to nucleos(t)ide analogues in chronic hepatitis B patients with normal alanine aminotransferase levels: a retrospective multi-center study

Rui Huang, Xingxiang Liu, Juan Xia, Tao Fan et al.
Emerging Microbes & Infections
Hepatitis B Virus Studies
article

Antiviral treatment response to nucleos(t)ide analogues in chronic hepatitis B patients with normal alanine aminotransferase levels: a retrospective multi-center study

Rui Huang, Xingxiang Liu, Juan Xia, Tao Fan, Fei Cao, Chuanwu Zhu, Jian Wang, Yuxin Chen, Zhiyi Zhang, Yu Shi, Yuanyuan Li, Xin‐Rong Zhang, Ye Xiong, Ying Zhang, Yifan Pan, Xiaomin Yan, Chao Jiang, Chao Wu, Shaoqiu Zhang, Li Zhu
article en

Abstract

CHB patients with normal ALT levels had comparable VR rates but significantly lower rates of HBeAg clearance and seroconversion during first-line NA therapy than patients with elevated ALT levels.

Emerging Microbes & InfectionsVol. 14(1)
Jiangsu University (CN), Nanjing University of Chinese Medicine (CN), Palo Alto University (US), Soochow University (TW), Jiangsu Second Normal University (CN), Soochow University (CN), Nanjing Drum Tower Hospital (CN), Stanford Medicine (US), Second Affiliated Hospital of Nanjing Medical University (CN), State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University (CN), Nanjing Medical University (CN), Nanjing University (CN), Stanford University (US)
Openalex Percentile: Top 55%
Hepatitis B Virus Studies
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