Antiviral treatment response to nucleos(t)ide analogues in chronic hepatitis B patients with normal alanine aminotransferase levels: a retrospective multi-center study
CHB patients with normal ALT levels had comparable VR rates but significantly lower rates of HBeAg clearance and seroconversion during first-line NA therapy than patients with elevated ALT levels.
Authors
- Rui Huang (ORCID: https://orcid.org/0000-0002-3189-7960)
- Xingxiang Liu
- Juan Xia (ORCID: https://orcid.org/0000-0002-4966-7119)
- Tao Fan (ORCID: https://orcid.org/0000-0002-6097-2413)
- Fei Cao
- Chuanwu Zhu (ORCID: https://orcid.org/0000-0002-9113-2046)
- Jian Wang (ORCID: https://orcid.org/0000-0001-8812-4398)
- Yuxin Chen (ORCID: https://orcid.org/0000-0001-5955-687X)
- Zhiyi Zhang (ORCID: https://orcid.org/0000-0003-0442-5885)
- Yu Shi (ORCID: https://orcid.org/0000-0001-8878-1806)
- Yuanyuan Li (ORCID: https://orcid.org/0000-0002-9143-8029)
- Xin‐Rong Zhang (ORCID: https://orcid.org/0000-0002-6689-5754)
- Ye Xiong
- Ying Zhang (ORCID: https://orcid.org/0000-0003-3853-5070)
- Yifan Pan (ORCID: https://orcid.org/0000-0001-9029-3975)
- Xiaomin Yan (ORCID: https://orcid.org/0000-0001-7937-1733)
- Chao Jiang
- Chao Wu
- Shaoqiu Zhang (ORCID: https://orcid.org/0009-0001-6385-2644)
- Li Zhu (ORCID: https://orcid.org/0000-0003-1583-2670)
Institutions
- Jiangsu University (CN)
- Nanjing University of Chinese Medicine (CN)
- Palo Alto University (US)
- Soochow University (TW)
- Jiangsu Second Normal University (CN)
- Soochow University (CN)
- Nanjing Drum Tower Hospital (CN)
- Stanford Medicine (US)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
- Zhejiang University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
- Stanford University (US)
Publication Details
- Journal
- Emerging Microbes & Infections
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1080/22221751.2025.2589550
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00