Signal Transducers and Activators of Transcription 1 (STAT1), STAT2, and T Cells Mediate Interferon-Dependent Protection Against Neurobrucellosis
Our findings indicate that T cells and IFN signaling through both STAT1 and STAT2 play complex and important roles in protecting against bacterial colonization and development of neurologic symptoms following infection by Brucella.
Authors
- Christa D. Jackson (ORCID: https://orcid.org/0000-0002-4152-2222)
- Mostafa F. N. Abushahba (ORCID: https://orcid.org/0000-0002-3616-3800)
- Irina Kochetkova (ORCID: https://orcid.org/0000-0002-1594-427X)
- Charles R. Moley (ORCID: https://orcid.org/0000-0002-1783-3450)
- Jerod A. Skyberg (ORCID: https://orcid.org/0000-0002-2337-908X)
- Bárbara Ponzilacqua-Silva (ORCID: https://orcid.org/0000-0001-5679-5242)
Institutions
- Montana State University (US)
- Missouri College (US)
- University of Missouri (US)
- Assiut University (EG)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1093/infdis/jiaf565
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health