Paediatric bladder melanosis: a rare case report

Bladder melanosis is a rare, typically benign histological finding involving melanin pigment deposition in the urothelium without melanocytes. Fewer than 40 reported cases exist, with only one prior paediatric case report. We present a 13-year-old male with a history of posterior urethral valves and ongoing bladder dysfunction. Cystoscopy showed brown bladder pigmentation and biopsy confirmed bladder melanosis with melanin pigment and chronic inflammation but no atypia or malignancy. Follow-up showed resolution with no specific treatment required. This is only the second reported paediatric case and highlights the importance of histological evaluation to confirm diagnosis and exclude malignancy.

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Publication Details

Journal
Urology Case Reports
Published
2025-11-13
DOI
https://doi.org/10.1016/j.eucr.2025.103266
Primary Topic
Urinary and Genital Oncology Studies
Type
article
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article

Paediatric bladder melanosis: a rare case report

Thivya Sekar, Alexander Cho, S. Pérez Sánchez, Athanasios Tyraskis et al.
Urology Case Reports
Urinary and Genital Oncology Studies
article

Paediatric bladder melanosis: a rare case report

Thivya Sekar, Alexander Cho, S. Pérez Sánchez, Athanasios Tyraskis, Suzannah Woodhouse
article en

Abstract

Bladder melanosis is a rare, typically benign histological finding involving melanin pigment deposition in the urothelium without melanocytes. Fewer than 40 reported cases exist, with only one prior paediatric case report. We present a 13-year-old male with a history of posterior urethral valves and ongoing bladder dysfunction. Cystoscopy showed brown bladder pigmentation and biopsy confirmed bladder melanosis with melanin pigment and chronic inflammation but no atypia or malignancy. Follow-up showed resolution with no specific treatment required. This is only the second reported paediatric case and highlights the importance of histological evaluation to confirm diagnosis and exclude malignancy.

Urology Case ReportsVol. 64
Great Ormond Street Hospital (GB), University College London (GB)
Openalex Percentile: Top 47%
Urinary and Genital Oncology Studies
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