Simulation of evoked responses to transcranial magnetic stimulation using a multiscale cortical circuit model
This validated multiscale model provides mechanistic insights into TMS-evoked cortical dynamics, demonstrating how direct neuronal activation cascades through synaptic networks to generate characteristic population responses. The framework establishes a computational platform for optimizing stimulation protocols in research and clinical applications.
Authors
- Alexander Opitz (ORCID: https://orcid.org/0000-0002-4851-1243)
- Zhihe Zhao (ORCID: https://orcid.org/0009-0009-6866-8027)
- Aman S. Aberra (ORCID: https://orcid.org/0000-0002-4805-541X)
Institutions
- Dartmouth College (US)
- University of Minnesota (US)
- Dartmouth Hospital (GB)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1016/j.brs.2025.11.010
- Citations
- 1
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Institute of Biomedical Imaging and Bioengineering