A binary prototype for time-series surveillance and intervention

Despite much research on early detection of anomalies from surveillance data, a systematic framework for appropriately acting on these signals is lacking. We addressed this gap by formulating a hidden Markov-style model for time-series surveillance, where the system state, the observed data, and the decision rule are all binary. We incur a delayed cost, c, whenever the system is abnormal and no action is taken, or an immediate cost, k, with action, where k<c. If action costs are too high, then surveillance is detrimental, and intervention should never occur. If action costs are sufficiently low, then surveillance is detrimental, and intervention should always occur. Only when action costs are intermediate and surveillance costs are sufficiently low is surveillance beneficial. Our equations provide a framework for assessing which approach may apply under a range of scenarios and, if surveillance is warranted, facilitate methodical classification of intervention strategies. Our model thus offers a conceptual basis for designing real-world public health surveillance systems.

Authors

Institutions

Publication Details

Journal
Epidemics
Published
2025-11-13
DOI
https://doi.org/10.1016/j.epidem.2025.100866
Citations
1
Primary Topic
Data-Driven Disease Surveillance
Type
article
Field-Weighted Citation Impact
1.35
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A binary prototype for time-series surveillance and intervention

Artem Boltyenkov, Rangarajan Sampath, Yonatan H. Grad, Marc Lipsitch et al.
1 citations
Epidemics
Data-Driven Disease Surveillance
1.35
article

A binary prototype for time-series surveillance and intervention

Artem Boltyenkov, Rangarajan Sampath, Yonatan H. Grad, Marc Lipsitch, Ankit Gupta, Jason Olejarz, Antonia Zapf, Till Hoffmann, Ross J. Molinaro, Douaa Mugahid, Sarah M. Fortune, Rifat Atun, Jukka-Pekka Onnela, Chloë Brown, Taras Dudykevych
article en
1 citations

Abstract

Despite much research on early detection of anomalies from surveillance data, a systematic framework for appropriately acting on these signals is lacking. We addressed this gap by formulating a hidden Markov-style model for time-series surveillance, where the system state, the observed data, and the decision rule are all binary. We incur a delayed cost, c, whenever the system is abnormal and no action is taken, or an immediate cost, k, with action, where k<c. If action costs are too high, then surveillance is detrimental, and intervention should never occur. If action costs are sufficiently low, then surveillance is detrimental, and intervention should always occur. Only when action costs are intermediate and surveillance costs are sufficiently low is surveillance beneficial. Our equations provide a framework for assessing which approach may apply under a range of scenarios and, if surveillance is warranted, facilitate methodical classification of intervention strategies. Our model thus offers a conceptual basis for designing real-world public health surveillance systems.

EpidemicsVol. 53
Harvard University (US), Siemens Healthcare (United States) (US), Siemens Healthineers (Germany) (DE), Harvard Global Health Institute (US)
Openalex Percentile: Top 14%
Data-Driven Disease Surveillance
1.35
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.