Does Lactate Dehydrogenase Act as an Early Warning System Predicting Mortality in Trauma Patients?

Aim: Trauma is one of the most prevalent causes of death and disability in middle age, and early diagnosis and treatment are critical in minimizing mortality and morbidity.Lactate dehydrogenase (LDH) is an indicator of inflammation in many diseases.We aim to present this study, in which we measure the power of LDH to show us mortality in the blood sample taken at the first examination in trauma patients, in the light of the literature. Materials and Methods:Trauma patients of emergency medicine department between November 2020 and November 2021, were analyzed.Trauma mechanism, consultations, mortality-morbidity, and scoring were evaluated retrospectively. Results:The glasgow coma scale (GCS), injury severity score (ISS), and new injury severity score (NISS) values of the patients were 14.581.76(95% confidence interval: 14.43-14.73),14 (0-76), and 18 (0-101) respectively.The data for leukocytes, hemoglobin, platelets, glucose, aspartate aminotransferase (AST), and LDH were significantly different between the control and patient groups.The comparison of leukocyte, hemoglobin, glucose, creatinine, AST, and LDH data between the survivors and the deceased in the patient group revealed a statistically significant difference.ROC analysis was then applied to evaluate these markers in the non-surviving patients.ISS, NISS, GCS, alanine aminotransferase, AST and LDH were found to be significant. Conclusion:LDH elevation, which is studied between routine procedures, may be beneficial for physicians working in the periphery both in patient referral and in making an early operation decision.Thus, we believe that mortality and morbidity will decrease with the use of LDH, a cost-effective marker.