Brain MRI findings in patients with post COVID-19 condition: frequency and longitudinal changes in a nationwide cohort study

Our findings indicate that brain MRI primarily serves to exclude differential diagnoses in post COVID-19 condition, with limited clinical benefit of repeated imaging in the absence of new symptoms. However, signs of long-term inflammatory processes can be observed, and detection is improved by contrast enhanced sequences.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-11-13
DOI
https://doi.org/10.3389/fneur.2025.1662263
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Brain MRI findings in patients with post COVID-19 condition: frequency and longitudinal changes in a nationwide cohort study

Einar August Høgestøl, Kenneth Ottesen Pedersen, Barbara Ratajczak‐Tretel, Øivind Torkildsen et al.
Frontiers in Neurology
Long-Term Effects of COVID-19
article

Brain MRI findings in patients with post COVID-19 condition: frequency and longitudinal changes in a nationwide cohort study

Einar August Høgestøl, Kenneth Ottesen Pedersen, Barbara Ratajczak‐Tretel, Øivind Torkildsen, Kristina Devik, Anne Hege Aamodt, Oliver Marcel Geier, Ragnhild Marie Undseth, Anette Huuse Farmen, Åse Hagen Morsund, Hanne F. Harbo, Christian Samsonsen, Vojtěch Novotný, Trine Haug Popperud, Marion Boldingh, Heidi Øyen Flemmen, Mona K. Beyer, Hilde Karen Ofte, Elisabeth Stokke Lindland, Per Selnes, Oksana Lapina, Liv Lygre Furevik
article en

Abstract

Our findings indicate that brain MRI primarily serves to exclude differential diagnoses in post COVID-19 condition, with limited clinical benefit of repeated imaging in the absence of new symptoms. However, signs of long-term inflammatory processes can be observed, and detection is improved by contrast enhanced sequences.

Frontiers in NeurologyVol. 16
Oslo University Hospital (NO), University of Liverpool (GB), University of Oslo (NO), Norwegian University of Science and Technology (NO), Innlandet Hospital Trust (NO), Akershus University Hospital (NO), Haukeland University Hospital (NO), Nordland Hospital Trust (NO), Namsos Hospital (NO), Molde Hospital (NO), Sørlandet Hospital Arendal (NO), St Olav's University Hospital (NO), Telemark Hospital (NO), Østfold Hospital Trust (NO), University of Bergen (NO)
Universitetet i Oslo
Openalex Percentile: Top 53%
Long-Term Effects of COVID-19
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