Deep Residual Xception Network-Based Lung Cancer Detection Using CT Images

Lung cancer (LC) is one of the major causes of death worldwide. Early diagnosis helps to improve the patient survival outcome. The surgeon makes use of Computed Tomography (CT) for detecting LC using the aid of a Computer-Aided Diagnosis (CAD) system to identify LC effectively, but it has issues related to processing time and diagnostic precision that continue to pose significant challenges. To address this, a Deep Residual Xception Network (DRX-Net) approach has been introduced for identifying the LC. Initially, the CT image is obtained and then denoising is performed using a Wiener filter. Subsequently, the segmentation of lung nodule is conducted using Pyramidal Attention-based Y Net (PAY-Net), which uses a hybrid loss function combining Binary Cross Entropy, Tanimoto Similarity, and Dice Loss. The segmented image undergoes data augmentation followed by feature extraction. For LC detection, the selected features are processed using DRX-Net, which merges the Xception with a Deep Residual Network (DRN). Furthermore, the results show that the proposed DRX-Net achieved an accuracy of 93.988%, a True Positive Rate (TPR) of 95.567%, and a True Negative Rate (TNR) of 91.432% when evaluated using a K Group of 8.

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Publication Details

Journal
Cancer Investigation
Published
2025-11-13
DOI
https://doi.org/10.1080/07357907.2025.2580957
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep Residual Xception Network-Based Lung Cancer Detection Using CT Images

V. V. K. D. V. Prasad, Deena Gnanasekaran, S. Balasubramaniam, Ilavarasan Sargunan et al.
Cancer Investigation
Lung Cancer Diagnosis and Treatment
article

Deep Residual Xception Network-Based Lung Cancer Detection Using CT Images

V. V. K. D. V. Prasad, Deena Gnanasekaran, S. Balasubramaniam, Ilavarasan Sargunan, Balashanmuga Vadivu Palanivel, Sriramakrishnan Gopalsamy Venkadakrishnan
article en

Abstract

Lung cancer (LC) is one of the major causes of death worldwide. Early diagnosis helps to improve the patient survival outcome. The surgeon makes use of Computed Tomography (CT) for detecting LC using the aid of a Computer-Aided Diagnosis (CAD) system to identify LC effectively, but it has issues related to processing time and diagnostic precision that continue to pose significant challenges. To address this, a Deep Residual Xception Network (DRX-Net) approach has been introduced for identifying the LC. Initially, the CT image is obtained and then denoising is performed using a Wiener filter. Subsequently, the segmentation of lung nodule is conducted using Pyramidal Attention-based Y Net (PAY-Net), which uses a hybrid loss function combining Binary Cross Entropy, Tanimoto Similarity, and Dice Loss. The segmented image undergoes data augmentation followed by feature extraction. For LC detection, the selected features are processed using DRX-Net, which merges the Xception with a Deep Residual Network (DRN). Furthermore, the results show that the proposed DRX-Net achieved an accuracy of 93.988%, a True Positive Rate (TPR) of 95.567%, and a True Negative Rate (TNR) of 91.432% when evaluated using a K Group of 8.

Cancer InvestigationVol. 43(10)
SRM Institute of Science and Technology (IN), Institute of Engineering (NP), Central University of Haryana (IN), Saveetha University (IN), Vellore Institute of Technology University (IN)
Openalex Percentile: Top 51%
Lung Cancer Diagnosis and Treatment
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Deep Residual Xception Network-Based Lung Cancer Detection Using CT Images — V. V. K. D. V. Prasad, Deena Gnanasekaran, et al. · Cancer Investigation (2025) | TGRS Research Map | TGRS