Salvia miltiorrhiza (Danshen) promotes Achilles tendon repair: from network pharmacology prediction to in vivo mechanistic validation
Tan IIA is the key bioactive component of Salvia miltiorrhiza for repairing Achilles tendon injury. It effectively promotes the structural and functional healing of the tendon by synergistically regulating key processes such as inflammation, matrix remodeling, and angiogenesis.
Authors
- Huiguo Wang
- Jinque Luo (ORCID: https://orcid.org/0000-0002-2744-2867)
- Gaoyuan Yang
- Ziyan Li (ORCID: https://orcid.org/0000-0001-5551-594X)
- Yu Wang (ORCID: https://orcid.org/0000-0002-6467-4536)
- Jia Xiaoxu
- Shuqi Qin (ORCID: https://orcid.org/0000-0001-5328-7488)
- Yifeng Li (ORCID: https://orcid.org/0009-0002-6994-9276)
- Lin Zhu (ORCID: https://orcid.org/0000-0003-2463-1686)
- Xianyan Xie
Institutions
- Guangzhou Sport University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3389/fphar.2025.1673962
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Southern Medical University